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Center for Quantitative Genome Function Biology and Social Science

Tadpoles

MSI Publications

MSI Publications

Brent R: (2004) Building an artificial regulatory system to understand a natural one. Cell, 116:S73-74, 71 p following S76. [ PubMed ]

Brent R: (2004) Intuition and innumeracy. Cell Biol Educ, 3:88-90. [ PubMed ]

Brent R: (2004) A partnership between biology and engineering. Nat Biotechnol, 22:1211-1214.
[ PubMed ]

Brent R: (2000) Genomic biology. Cell, 100:169-183. [ PubMed ]

Brent R: (1999) Functional genomics: learning to think about gene expression data. Curr Biol, 9:R338-341. [ PubMed ]

Brent R: (1997) Looms to weave genomic nets. Nat Genet, 16:216-217. [ PubMed ]

Brent R, Bruck J: (2006) 2020 computing: can computers help to explain biology? Nature, 440:416-417. [ PubMed ]

Brent R, Burbulis I: (2005) Reply to "Lamp for tadpoles". Nature Methods, 2:635-636. [ PubMed ]

Brent R, Finley RL, Jr.: (1997) Understanding gene and allele function with two-hybrid methods. Annu Rev Genet, 31:663-704. [ PubMed ]

Brent R, Kodadek T: (2000) Interaction, Assembly and Processing: Life on the Interface. Curr Opin Chem Bio, 4:13-15.

Brent R, Lok L: (2005) Cell biology. A fishing buddy for hypothesis generators. Science, 308:504-506.
[ PubMed ]

Burbulis, I., Yamaguchi, K., Yu, R., Resnekov O., and Brent, R. (2007) Quantifying small numbers of molecules with a “near-universal” protein-DNA chimera. Nat Methods. , 12:1011-3 .

Burbulis I, Yamaguchi K, Gordon A, Carlson R, Brent R: (2005) Using protein-DNA chimeras to detect and count small numbers of molecules. Nat Methods, 2:31-37. [ PubMed ]

Burbulis IE, Winkel-Shirley B: (1999) Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway. Proc Natl Acad Sci U S A, 96:12929-12934. [ PubMed ]

Carlson R, Brent R: (1999) Double-stranded DNA arrays: next steps in the surface campaign. Nat Biotechnol, 17:536-537. [ PubMed ]

Chin TE, Wong RB, Pont JL, Karu AE: (2002) Haptens and monoclonal antibodies for immunoassay of imidazolinone herbicides. J Agric Food Chem, 50:3380-3389. [ PubMed ]

Cohen BA, Colas P, Brent R: (1998) An artificial cell-cycle inhibitor isolated from a combinatorial library. Proc Natl Acad Sci U S A, 95:14272-14277. [ PubMed ]

Colas P, Brent R: (1998) The impact of two-hybrid and related methods on biotechnology. Trends Biotechnol, 16:355-363. [ PubMed ]

Colas P, Cohen B, Jessen T, Grishina I, McCoy J, Brent R: (1996) Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2. Nature, 380:548-550. [ PubMed ]

Colas P, Cohen B, Ko Ferrigno P, Silver PA, Brent R: (2000) Targeted modification and transportation of cellular proteins. Proc Natl Acad Sci U S A, 97:13720-13725. [ PubMed ]

Colman-Lerner A, Brent R: (2000) Using peptide aptamers to analyze the proteome. Trends Cell Bio:56-60.

Colman-Lerner A, Chin TE, Brent R: (2001) Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell, 107:739-750. [ PubMed ]

Colman-Lerner A, Fischman ML, Lanuza GM, Bissell DM, Kornblihtt AR, Baranao JL: (1999) Evidence for a role of the alternatively spliced ED-I sequence of fibronectin during ovarian follicular development. Endocrinology, 140:2541-2548. [ PubMed ]

Colman-Lerner A, Gordon A, Serra E, Chin T, Resnekov O, Endy D, Pesce CG, Brent R (2005) Regulated cell-to-cell variation in a cell-fate decision system. Nature, 437:699-706.
[ PubMed ]

Crater DL, Wade KH, Resnekov O, Ichikawa HT, Kroos L, Brannigan JA, Moran CP, Jr.: (2002) A mutation in GerE that affects cotC promoter activation in Bacillus subtilis. Biochim Biophys Acta, 1576:30-38. [ PubMed ]

Dehlin E, von Gabain A, Alm G, Dingelmaier R, Resnekov O: (1996) Repression of beta interferon gene expression in virus-infected cells is correlated with a poly(A) tail elongation. Mol Cell Biol, 16:468-474. [ PubMed ]

Endy D, Brent R: (2001) Modelling cellular behaviour. Nature, 409:391-395. [ PubMed ]

Fabbrizio E, Le Cam L, Polanowska J, Kaczorek M, Lamb N, Brent R, Sardet C: (1999) Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity. Oncogene, 18:4357-4363. [ PubMed ]

Finley RL, Jr., Brent R: (1994) Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators. Proc Natl Acad Sci U S A, 91:12980-12984. [ PubMed ]

Fung TH, Ball GI, McQuiade SC, Chao S-H, Colman-Lerner A, Holl M, Meldrum DR: Microprinting on On-chip Cultures: Patterning of Yeast Cell Microarrays using Concalavin-A Adhesion. In ASME International Mechanical Engineering Congress; Anaheim, CA: American Society of Mechanical Engineers: 2004.

Geyer CR, Brent R: (2000) Selection of genetic agents from random peptide aptamer expression libraries. Methods Enzymol, 328:171-208. [ PubMed ]

Geyer CR, Colman-Lerner A, Brent R: (1999) "Mutagenesis" by peptide aptamers identifies genetic network members and pathway connections. Proc Natl Acad Sci U S A, 96:8567-8572. [ PubMed ]

Gordon A, Colman-Lerner A, Chin TE, Benjamin KR, Yu, R.C., Brent R: (2007) Single-cell quantification of molecules and rates using open-source microscope-basd cytometry. Nat Methods.

Krainc D, Bai G, Okamoto S, Carles M, Kusiak JW, Brent RN, Lipton SA: (1998) Synergistic activation of the N-methyl-D-aspartate receptor subunit 1 promoter by myocyte enhancer factor 2C and Sp1. J Biol Chem, 273:26218-26224. [ PubMed ]

Lin JH, Makris A, McMahon C, Bear SE, Patriotis C, Prasad VR, Brent R, Golemis EA, Tsichlis PN: (1999) The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1. J Biol Chem, 274:14706-14715. [ PubMed ]

Lok L: (2004) The need for speed in stochastic simulation. Nat Biotechnol, 22:964-965. [ PubMed

Lok L: (2002) Pathfinder and other tools for analyzing signal transduction networks. Ann N Y Acad Sci, 971:589-594. [ PubMed ]

Lok L, Brent R: (2005) Response to "On-the-fly" or "generate first" modeling. Nat Biotechnol, 23:1345.

Lok L, Brent R: (2005) Automatic generation of cellular reaction networks with Moleculizer 1.0. Nat Biotechnol, 23:131-136. [ PubMed ]

Marti F, Xu CW, Selvakumar A, Brent R, Dupont B, King PD: (1998) LCK-phosphorylated human killer cell-inhibitory receptors recruit and activate phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A, 95:11810-11815. [ PubMed ]

Mendelsohn AR, Brent R: (1998) Postgenomic protein analysis: the next bend in the river. Nat Biotechnol, 16:520-521. [ PubMed ]

Mendelsohn AR, Brent R: (1994) Applications of interaction traps/two-hybrid systems to biotechnology research. Curr Opin Biotechnol, 5:482-486. [ PubMed ]

Mendelsohn AR, Hamer JD, Wang ZB, Brent R: (2002) Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death. Proc Natl Acad Sci U S A, 99:6871-6876. [ PubMed ]

Meroni G, Cairo S, Merla G, Messali S, Brent R, Ballabio A, Reymond A: (2000) Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway? Oncogene, 19:3266-3277. [ PubMed ]

Raj L, Vivekanand P, Das TK, Badam E, Fernandes M, Finley RL, Brent R, Appel LF, Hanes SD, Weir M: (2000) Targeted localized degradation of Paired protein in Drosophila development. Curr Biol, 10:1265-1272. [ PubMed ]

Resnekov O: (1999) Role of the sporulation protein BofA in regulating activation of the Bacillus subtilis developmental transcription factor sigmaK. J Bacteriol, 181:5384-5388. [ PubMed ]

Resnekov O, Alper S, Losick R: (1996) Subcellular localization of proteins governing the proteolytic activation of a developmental transcription factor in Bacillus subtilis. Genes Cells, 1:529-542. [ PubMed ]

Resnekov O, Driks A, Losick R: (1995) Identification and characterization of sporulation gene spoVS from Bacillus subtilis. J Bacteriol, 177:5628-5635. [ PubMed ]

Resnekov O, Losick R: (1998) Negative regulation of the proteolytic activation of a developmental transcription factor in Bacillus subtilis. Proc Natl Acad Sci U S A, 95:3162-3167. [ PubMed ]

Resnekov O, Melin L, Carlsson P, Mannerlov M, von Gabain A, Hederstedt L: (1992) Organization and regulation of the Bacillus subtilis odhAB operon, which encodes two of the subenzymes of the 2-oxoglutarate dehydrogenase complex. Mol Gen Genet, 234:285-296. [ PubMed ]

Takahashi K: (2005) Protein crowding and localization in cellular signaling systems (Japanese). HFSP Newsletter. [ PubMed ]

Takahashi K, Nanda S, Arjunan V, Tomita M: (2005) Space in systems biology of signaling pathways-towards intracellular molecular crowding in silico. FEBS Letters, 579:1783-1788.

Webb CD, Resnekov O: (1999) Use of green fluorescent protein for visualization for cell-specific gene expression and subcellular protein localization in Bacillus subtilis. Methods Enzymol, 302:136-153. [ PubMed ]

Xu CW, Mendelsohn AR, Brent R: (1997) Cells that register logical relationships among proteins. Proc Natl Acad Sci U S A, 94:12473-12478. [ PubMed ]

Yu, R.C., Pesce, C.G. , Colman-Lerner, A., Lok, L.,Pincus, D., Serra, E., Holl, M., Benjamin, K., Gordon, A., and Brent , R. (2008) feedback that improves information transmission in yeast signalling. Nature 456: 755-761.

Zervos AS, Gyuris J, Brent R: (1994) Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell, 79:following 388. [ PubMed ]

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