Ian Burbulis, Ph.D.
Senior Research Fellow
Email: harley molsci.org
Tel: 510-981-8752
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Biological systems, whether naturally occurring or synthetic,
are complex collections of parts executing dynamic biochemical
reactions. Deciphering the mechanistic operation of these systems
requires knowledge of the presence, quantity and activity of
different parts through time, ideally from single cells. My
interests broadly focus on the development of sensitive measurement
technologies to quantitatively describe the mechanistic operation
of biological systems. Ultimately, I seek to apply these tools
to the assessment of human health and disease. My research
specifically focuses on three areas (1) engineering composite
materials from biological molecules for use in biotechnology
applications, (2) developing signature assays for early detection
of human cancer, infection and health assessment, and (3) quantitatively
describing how decisions are computed during lymphocyte stimulation
and how viral challenge affects autoimmunity and cancer. Achieving
these goals will fundamentally advance our capability to formulate
quantitative models of dynamic biological systems.
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